Search results for "Outcome measure"

showing 10 items of 129 documents

The global impact of the COVID-19 pandemic on the management and course of chronic urticaria

2021

Introduction: the COVID-19 pandemic dramatically disrupts health care around the globe. The impact of the pandemic on chronic urticaria (CU) and its management are largely unknown. Aim: to understand how CU patients are affected by the COVID-19 pandemic; how specialists alter CU patient management; and the course of CU in patients with COVID-19. Materials and methods: our cross-sectional, international, questionnaire-based, multicenter UCARE COVID-CU study assessed the impact of the pandemic on patient consultations, remote treatment, changes in medications, and clinical consequences. Results: the COVID-19 pandemic severely impairs CU patient care, with less than 50% of the weekly numbers o…

Male0301 basic medicineSTRESSExacerbationUCAREpandemijeMedizinOmalizumabOmalizumabSERUMchronic urticaria0302 clinical medicinePandemicHealth careImmunology and AllergyChronic UrticariatreatmentChronic urticaria; COVID-19; Cyclosporine; Omalizumab; Pandemic; SARS-CoV-2; Treatment; UCAREzdravljenjeASSOCIATIONMiddle AgedCOVID-19; SARS-CoV-2; UCARE; chronic urticaria; cyclosporine; omalizumab; pandemic; treatmentkronična urtikarijaINFECTIONSGA(2)LENCyclosporineFemale600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheitmedicine.drugAdultmedicine.medical_specialtyAdolescentCoronavirus disease 2019 (COVID-19)Immunology610udc:616-097pandemicsciklosporinYoung Adult03 medical and health sciencesPatient referralmedicineHumansIn patientPatient Reported Outcome MeasurescyclosporineChronic urticariaAgedInternetPandemicSARS-CoV-2business.industrypandemicCOVID-19TreatmentDEFINITIONMedicine; Allergy; ImmunologyCross-Sectional Studies030104 developmental biology030228 respiratory systemEmergency medicineomalizumabbusinessAllergy: European Journal of Allergy and Clinical Immunology
researchProduct

Quality of Life in a German Graves Orbitopathy Population

2010

To evaluate the validity and responsiveness of a German-language version of the disease-specific Graves orbitopathy quality-of-life questionnaire (GO-QOL).Prospective cross-sectional study.At a multidisciplinary university orbital center, 310 consecutive unselected Graves orbitopathy outpatients answered the GO-QOL before undergoing complete ophthalmic and endocrine assessment. The main outcome measures were the GO-QOL and its 2 subscales, Visual Functioning and Appearance.The QOL scores for the subscales Visual Functioning and Appearance were (mean ± SE) 72.5 ± 1.4 and 71.3 ± 1.5, respectively. Visual Functioning and Appearance were higher in mild (82.2 ± 2.2 and 86.0 ± 17.6) than in moder…

AdultCross-Cultural ComparisonMaleModerate to severePediatricsmedicine.medical_specialtyValidation studyAdolescentCross-sectional studyPopulationYoung AdultQuality of lifeGermanySickness Impact ProfileSurveys and QuestionnairesActivities of Daily LivingOrbital DiseasesmedicineHumansProspective StudiesYoung adulteducationProspective cohort studyAgedLanguageAged 80 and overeducation.field_of_studybusiness.industryOutcome measuresMiddle AgedSurgeryGraves OphthalmopathyOphthalmologyCross-Sectional StudiesQuality of LifeFemalebusinessAmerican Journal of Ophthalmology
researchProduct

Validity and reliability of the motivation for physical activity (RM4-FM) questionnaire

2021

There is a lack of validated instruments measuring motivation for physical activity (RM4-FM) in the Finnish language. The study examined the translated RM4-FM instrument’s psychometric properties in a sample of healthy, older Finnish adults. RM4-FM was translated and linguistically validated adhering to published guidelines. 65–75-year olds (n=102), completed the RM4-FM, the physical activity acceptance questionnaire (PAAQ) and sociodemographic characteristics questionnaires electronically. The RM4-FM was readministered one month after the initial assessment. RM4-FM translated well into Finnish. Motivation dimension scores were skewed towards high internal and low external motivation. A flo…

030506 rehabilitationValidityPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicineFloor effectOrthopedics and Sports MedicineReliability (statistics)Self-determination theoryreliabiliteettimotivaatio030229 sport sciencesPatient-reported outcome measureExploratory factor analysisConfirmatory factor analysisSelf-determination theorypsykometriikkaPsychometric propertiesvaliditeettiScale (social sciences)mittarit (mittaus)Ceiling effectOriginal Article0305 other medical sciencePsychologyInactivityfyysinen aktiivisuusikääntyneetClinical psychologyJournal of Exercise Rehabilitation
researchProduct

Systematic review of the health-related quality of life issues facing adolescents and young adults with cancer

2017

Contains fulltext : 174665.pdf (Publisher’s version ) (Open Access) PURPOSE: For adolescents and young adults (AYAs), the impact of a cancer diagnosis and subsequent treatment is likely to be distinct from other age groups given the unique and complex psychosocial challenges of this developmental phase. In this review of the literature, we report the health-related quality of life (HRQoL) issues experienced by AYAs diagnosed with cancer and undergoing treatment. METHODS: MEDLINE, EMBASE, CINAHL, PsychINFO and the Cochrane Library Databases were searched for publications reporting HRQoL of AYAs. Issues generated from interviews with AYAs or from responses to patient reported outcome measures…

AdultGerontologymedicine.medical_specialtyAdolescentReviewYoung Adult03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Age groupsNeoplasmsmedicinecancerHumansPatient reported outcome measures (PROMs)Patient Reported Outcome Measures030212 general & internal medicineYoung adultPsychiatryCancerQuality of Life ResearchHealth related quality of lifebusiness.industryPublic healthPublic Health Environmental and Occupational HealthCancermedicine.diseaseHealth-related quality of life (HRQoL)humanitiesadolescents and young adults (AYAs)030220 oncology & carcinogenesisQuality of LifeAdolescents and young adults (AYAs)health-related quality of life (HRQoL)businessPsychosocialpatient reported outcome measures (PROMs)Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
researchProduct

Kinetics of the early development of uniparental human haploid embryos

2016

Objective: To describe morphokinetically the early development of human haploid parthenotes and androgenotes and to compare them with euploid embryos. Design: Experimental study of kinetics. Setting: University-affiliated private fertility center. Patient(s): Experimental haploid parthenotes and androgenotes. Intervention(s): Kinetic study of early development (up to eight cells) of 8 parthenotes, 10 androgenotes, and 20 euploid embryos. Main Outcome Measure(s): Timing of the first seven cleavages determined according to embryo origin, then calculation of the duration of the second and third cell cycles (cc2 and cc3) of whole embryos and individual cells. Result(s): Parthenotes and androgen…

0301 basic medicineAdultanimal structuresAdolescentmedicine.medical_treatmentEmbryonic DevelopmentBiologyHaploidyIntracytoplasmic sperm injectionAndrology03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansSperm Injections IntracytoplasmichumanGenetics030219 obstetrics & reproductive medicineOutcome measuresObstetrics and GynecologyEmbryoOocyte activationAndrogenoteAneuploidyKineticshaploid030104 developmental biologyReproductive Medicinemorphokineticparthenoteembryonic structuresPloidy
researchProduct

The Challenges of the European Anorectal Malformations-Net Registry

2015

Item does not contain fulltext Anorectal malformations (ARM) have a low prevalence, patients need specialized surgical care, and in many cases, patients born with ARM even need life-long aftercare. Due to its low prevalence most patients are still treated in low-volume pediatric surgical centers without any adequate monitoring of the outcome. Data on prevalence, comparison of different surgical techniques, and prospective outcome measurements are still scarce and difficult to interpret. In 2010, a consortium was founded (ARM-Net consortium) including several European pediatric surgical centers to collaborate more in research and share knowledge on ARM. One of the structures started by the c…

Registrymedicine.medical_specialtyPediatricsOutcome measurementsbusiness.industryGeneral surgerySurgical careRectumAnal CanalNetworkAnorectal malformationAnorectal MalformationsRare diseasesAnorectal malformation; Network; Rare diseases; RegistryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Anus ImperforateEuropeReconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10]Pediatrics Perinatology and Child HealthStill facemedicineHumansSurgeryRegistriesbusinessEuropean Journal of Pediatric Surgery
researchProduct

Effectiveness of Neural Mobilization Techniques in the Management of Musculoskeletal Neck Disorders with Nerve-Related Symptoms: A Systematic Review …

2021

Abstract Objective The objective was to assess the effectiveness of neural mobilization (NM) techniques in the management of musculoskeletal neck disorders with nerve-related symptoms (MND-NRS). Methods We conducted a systematic review with meta-analysis, using pain intensity, disability, perceived function, cervical range of motion, and mechanosensitivity as the main outcome measures. Results The systematic review included 22 studies (n = 978). More favorable outcomes were observed for NM on pain intensity compared with control interventions (standardized mean differences (SMDs) −0.92; 95% CI −1.66−0.18), but not compared with other treatments (OTs) (SMD 1.06; 95% CI −0.02 to 2.15). Regard…

Cervical range of motionmedicine.medical_specialtyNeck painNeck Painbusiness.industryOutcome measuresPsychological interventionNeck rotationGeneral MedicineIntensity (physics)Anesthesiology and Pain MedicineNeural mobilizationMeta-analysisPhysical therapymedicineHumansMusculoskeletal DiseasesNeurology (clinical)Range of Motion Articularmedicine.symptombusinessNeckPhysical Therapy ModalitiesPain Medicine
researchProduct

Rank response functions in an online learning environment

2021

Abstract We estimate rank response functions after receiving rank-order feedback in an online learning platform. We find that the shapes of the rank response functions depend on the outcome measure under consideration. For our effort measure, i.e., whether learners continue to interact with the platform, we can reject a linear rank response function and find significant evidence of a U-shaped relationship. For our performance measure, i.e., correctly solved exercises, we find no clear pattern overall but suggestive evidence for a linearly decreasing rank response function for individuals in the lower half of the ability distribution, i.e., the lower the rank the lower the performance.

Economics and EconometricsDistribution (mathematics)Online learningRank (computer programming)StatisticsOutcome measuresFunction (mathematics)Measure (mathematics)Lower halfFinanceMathematicsEconomics Letters
researchProduct

Psychometric properties of the Finnish version of the Young Person's Clinical Outcomes in Routine Evaluation (YP-CORE) questionnaire.

2017

An increasing need exists for suitable measures to evaluate treatment outcome in adolescents. YP-CORE is a pan-theoretical brief questionnaire developed for this purpose, but it lacks studies in different cultures or languages.To explore the acceptability, factor structure, reliability, validity, and sensitivity to change of the Finnish translation of YP-CORE.The study was conducted at the Department of Adolescent Psychiatry, Helsinki University Central Hospital. A Finnish translation was prepared by a team of professionals and adolescents. A clinical sample of 104 patients was asked to complete the form together with BDI-21 and BAI, and 92 of them filled the forms again after a 3-month tre…

Self-assessmentCross-Cultural ComparisonMale050103 clinical psychologymedicine.medical_specialtySelf-AssessmentPsychometricsAdolescentPsychometricsConcurrent validitypsychometric properties03 medical and health sciencesoutcome measures0302 clinical medicineSurveys and QuestionnairesYP-COREOutcome Assessment Health CaremedicineHumans0501 psychology and cognitive sciencesPsychiatryReliability (statistics)ta515Finlandbusiness.industryMental Disorders05 social sciencesBeck Depression InventoryYoung Person’s Clinical Outcomes in Routine EvaluationReproducibility of ResultsquestionnairesTranslatingCross-cultural studiesroutine evaluationConfirmatory factor analysisclinical outcomes3. Good health030227 psychiatryPsychiatry and Mental healthAnxietyadolescenceFemalemedicine.symptombusinessNordic journal of psychiatry
researchProduct

Italian version of the Chicago multiscale depression inventory: translation, adaptation and testing in people with multiple sclerosis.

2004

Depression is the commonest psychiatric disturbance in people with multiple sclerosis (MS), with prevalence higher than in the general population and other chronic diseases. However, accurate assessment of depressive symptoms can be biased by somatic symptoms which are part of both MS and depression. We translated and adapted into Italian the Chicago multiscale depression inventory (CMDI) and assessed its acceptability, internal consistency and test-retest reliability in 213 MS outpatients and 213 individually matched healthy controls. The questionnaire was also tested in 32 people with major depression. Acceptability, internal consistency, and test-retest reliability were good overall. We …

AdultMalemedicine.medical_specialtyMultiple SclerosisPsychometricsAdolescentPersonality InventoryPsychometricsMultiple sclerosis Depression Outcome measures MoodeducationPopulationDermatologySurveys and QuestionnairesOutcome Assessment Health CaremedicineHumanseducationPsychiatryDepression (differential diagnoses)Psychiatric Status Rating Scaleseducation.field_of_studyDepressionMultiple sclerosisCase-control studyAge FactorsReproducibility of ResultsGeneral MedicineOdds ratioMiddle Agedmedicine.diseasePsychiatry and Mental healthMoodItalyEvaluation Studies as TopicCase-Control StudiesFemaleNeurology (clinical)Personality Assessment InventoryPsychologyClinical psychologyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
researchProduct